The KDM6A Antibody (Center) from MyBioSource.com is a Rabbit Polyclonal antibody to KDM6A, and UTX. This antibody recognizes Human antigen. The KDM6A Antibody (Center) has been validated for the following applications: ELISA, and Western Blot.
Description
Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A